BDBM50110504 3-(2-tert-Butyl-4,4-dimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile::CHEMBL349398

SMILES CC(C)(C)C1Nc2ccc(cc2C(C)(C)O1)-c1cc(F)cc(c1)C#N

InChI Key InChIKey=DJETUOJRHYCFLA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110504   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110504(3-(2-tert-Butyl-4,4-dimethyl-1,4-dihydro-2H-benzo[...)
Affinity DataIC50: 3.04E+3nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110504(3-(2-tert-Butyl-4,4-dimethyl-1,4-dihydro-2H-benzo[...)
Affinity DataIC50: 127nMAssay Description:Antagonistic activity against Progesterone receptor (PR) in transcriptional activation assay in human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110504(3-(2-tert-Butyl-4,4-dimethyl-1,4-dihydro-2H-benzo[...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed