BDBM50110496 6-(3-Chloro-phenyl)-4,4-dimethyl-2-trifluoromethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine::CHEMBL164082

SMILES CC1(C)OC(Nc2ccc(cc12)-c1cccc(Cl)c1)C(F)(F)F

InChI Key InChIKey=WCLGFCXIOBIRSU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110496   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110496(6-(3-Chloro-phenyl)-4,4-dimethyl-2-trifluoromethyl...)
Affinity DataEC50:  2.90nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110496(6-(3-Chloro-phenyl)-4,4-dimethyl-2-trifluoromethyl...)
Affinity DataIC50: 41nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed