BDBM50110495 3-(4,4-Dimethyl-2-trifluoromethyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile::CHEMBL167570

SMILES CC1(C)OC(Nc2ccc(cc12)-c1cc(F)cc(c1)C#N)C(F)(F)F

InChI Key InChIKey=NZOHVKQNZLFMHA-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110495   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110495(3-(4,4-Dimethyl-2-trifluoromethyl-1,4-dihydro-2H-b...)
Affinity DataIC50: 7.10nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50110495(3-(4,4-Dimethyl-2-trifluoromethyl-1,4-dihydro-2H-b...)
Affinity DataEC50:  1.70nMAssay Description:Agonistic activity against progesterone receptor in alkaline phosphatase assay using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed