BDBM50110486 3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-pyrazole::CHEMBL165946

SMILES CCCCc1cc(-c2ccccc2)n(n1)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=UYTGVWPXYLXVSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110486   

TargetProstaglandin G/H synthase 1(Human)
Laboratoires Innothera

Curated by ChEMBL
LigandPNGBDBM50110486(3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 1 using monocytes-like cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratoires Innothera

Curated by ChEMBL
LigandPNGBDBM50110486(3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Laboratoires Innothera

Curated by ChEMBL
LigandPNGBDBM50110486(3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-p...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 5-lipoxygenase activity of compound evaluated as determined by the inhibition of calcium ionophore-induced leukotriene B4 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed