BDBM50110480 CHEMBL166156::[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazol-3-yl]-methanol

SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(CO)cc1-c1ccccc1

InChI Key InChIKey=AKYAXJLSWCRMRL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110480   

TargetProstaglandin G/H synthase 1(Human)
Laboratoires Innothera

Curated by ChEMBL
LigandPNGBDBM50110480([1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 1 using monocytes-like cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Laboratoires Innothera

Curated by ChEMBL
LigandPNGBDBM50110480([1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-lipoxygenase activity of compound evaluated as determined by the inhibition of calcium ionophore-induced leukotriene B4 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Laboratoires Innothera

Curated by ChEMBL
LigandPNGBDBM50110480([1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed