BDBM50110387 4-{2-[(S)-5-((S)-2,3-Dihydro-benzofuran-5-sulfonylamino)-4-oxo-1,2,4,5,6,7-hexahydro-azepino[3,2,1-hi]indol-2-yl]-2-oxo-ethyl}-piperidine-1-carboxamidine::CHEMBL163312

SMILES NC(=N)N1CCC(CC(=O)[C@@H]2Cc3cccc4CC[C@H](NS(=O)(=O)c5ccc6OCCc6c5)C(=O)N2c34)CC1

InChI Key InChIKey=XJJMRYCODRNFRY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110387   

TargetTrypsin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50110387(4-{2-[(S)-5-((S)-2,3-Dihydro-benzofuran-5-sulfonyl...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory constant against trypsin determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50110387(4-{2-[(S)-5-((S)-2,3-Dihydro-benzofuran-5-sulfonyl...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against human thrombin (FIIa) determined in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50110387(4-{2-[(S)-5-((S)-2,3-Dihydro-benzofuran-5-sulfonyl...)
Affinity DataKi:  49nMAssay Description:Inhibitory constant against human Coagulation factor Xa determined in VitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed