BDBM50110199 4-(4-(4-fluorophenyl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzoic acid::4-[4-(4-Fluoro-phenyl)-5-pyridin-2-yl-1H-imidazol-2-yl]-benzoic acid::CHEMBL269339

SMILES OC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccccn1

InChI Key InChIKey=RQQBMRHOBFJBAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110199   

TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110199(4-(4-(4-fluorophenyl)-5-(pyridin-2-yl)-1H-imidazol...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Activin like receptor kinase 5, TGF beta type I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110199(4-(4-(4-fluorophenyl)-5-(pyridin-2-yl)-1H-imidazol...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50110199(4-(4-(4-fluorophenyl)-5-(pyridin-2-yl)-1H-imidazol...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonistic activity at TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed