BDBM50110189 CHEMBL3605296

SMILES O=C(N1CCc2nc(COc3ccccc3)oc2C1)c1n[nH]c2ncccc12

InChI Key InChIKey=CACDSTLXMIALPW-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110189   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50110189(CHEMBL3605296)
Affinity DataEC50:  550nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50110189(CHEMBL3605296)
Affinity DataEC50:  546nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50110189(CHEMBL3605296)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed