BDBM50110047 1-[1-(3-Cyclopentyloxy-4-difluoromethoxy-phenyl)-cyclopropylmethyl]-1,3-dihydro-imidazol-2-one::CHEMBL350482

SMILES FC(F)Oc1ccc(cc1OC1CCCC1)C1(Cn2cc[nH]c2=O)CC1

InChI Key InChIKey=MIWHWBZDGOPRTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110047   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50110047(1-[1-(3-Cyclopentyloxy-4-difluoromethoxy-phenyl)-c...)
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed