BDBM50110006 CHEMBL352009::N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hydroxy-2-(2-phenyl-ethenesulfonylamino)-propionamide

SMILES NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)\C=C\c2ccccc2)cc1

InChI Key InChIKey=BQFZJSMJQJWSFL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50110006   

TargetSerine protease 1(Human)
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110006(N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hyd...)
Affinity DataKi:  1.70E+3nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110006(N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hyd...)
Affinity DataKi:  2.20E+3nMAssay Description:In vitro inhibition of plasminogen activator urokinase after a 30 min incubation period.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110006(N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hyd...)
Affinity DataKi:  1.50E+4nMAssay Description:In vitro inhibition of thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110006(N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hyd...)
Affinity DataKi:  1.50E+4nMAssay Description:In vitro inhibition of Coagulation factor Xa.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110006(N-[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-3-hyd...)
Affinity DataKi:  1.40E+5nMAssay Description:In vitro inhibition of Plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed