BDBM50109897 (R)-3-(4-Cyclopentyloxy-phenyl)-3-{[(S)-1-(3,5-dichloro-benzenesulfonyl)-azetidine-2-carbonyl]-amino}-propionic acid::CHEMBL442769

SMILES OC(=O)C[C@@H](NC(=O)[C@@H]1CCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1)c1ccc(OC2CCCC2)cc1

InChI Key InChIKey=YHFWYPZHVJZULG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109897   

TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109897((R)-3-(4-Cyclopentyloxy-phenyl)-3-{[(S)-1-(3,5-dic...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against alpha-4 beta-1 receptor (VLA-4) in human RPMI-8866 cells using [125I]-VCAM-Ig ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed