BDBM50109856 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-dimethylamino-benzyl)-N'-cyano-piperidine-1-carboxamidine::CHEMBL440365

SMILES [#6]-[#7](-[#6])-c1ccc(-[#6]-[#7]-[#6](=[#7]C#N)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]-2\c3ccc(Cl)cc3-[#6]-[#6]-c3cc(Br)cnc-23)cc1

InChI Key InChIKey=PHBHFQINKILGAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109856   

LigandPNGBDBM50109856(4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohep...)
Affinity DataIC50: 100nMAssay Description:FPT inhibitory activity was determined by the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-ras-CLVSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed