BDBM50109840 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-(4-nitro-phenyl)-N'-cyano-piperidine-1-carboxamidine::CHEMBL158245

SMILES [O-][N+](=O)c1ccc(NC([N-]C#N)=[N+]2CCC(CC2)=C2c3ccc(Cl)cc3CCc3cc(Br)cnc23)cc1

InChI Key InChIKey=IHNGSYVRUWKKEX-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109840   

LigandPNGBDBM50109840(4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohep...)
Affinity DataIC50: 62nMAssay Description:FPT inhibitory activity was determined by the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-ras-CLVSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed