BDBM50109747 CHEMBL3604181

SMILES Clc1ccc2oc(nc2c1)-c1cc[nH]n1

InChI Key InChIKey=CTLFRZYSQHHTPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109747   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109747(CHEMBL3604181)
Affinity DataIC50: 443nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109747(CHEMBL3604181)
Affinity DataIC50: 124nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed