BDBM50109702 CHEMBL3604174

SMILES Clc1ccc(NC(=O)c2cn[nH]n2)c(Cl)c1

InChI Key InChIKey=GAGGCNZJYKWGJL-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50109702   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 78nMAssay Description:Inhibition of pig 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 500nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 5.81E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 99nMAssay Description:Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 56nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109702(CHEMBL3604174)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of rat 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed