BDBM50109648 CHEMBL3604161

SMILES Fc1ccc(NC(=O)c2n[nH]c(c2C(F)(F)F)C(F)(F)F)c(Cl)c1

InChI Key InChIKey=NSLGSSNRJNMZDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109648   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50109648(CHEMBL3604161)
Affinity DataIC50: 279nMAssay Description:Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed