BDBM50109326 (R)-1-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-propyl-pyridin-3-yl]-ethanol::1-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-propyl-pyridin-3-yl]-ethanol::CHEMBL25637

SMILES CCCc1c(nc(C(C)C)c([C@@H](C)O)c1-c1ccc(F)cc1)C(C)C

InChI Key InChIKey=XPINZAYSUKBJNK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109326   

TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50109326((R)-1-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-propy...)
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against cAMP production in hGR-CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50109326((R)-1-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-propy...)
Affinity DataIC50: 110nMAssay Description:Tested for its inhibitory activity against human glucagon receptor (hGR) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50109326((R)-1-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-propy...)
Affinity DataIC50: 110nMAssay Description:Binding affinity of first diastereomer (D1) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50109326((R)-1-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-5-propy...)
Affinity DataIC50: 65nMAssay Description:Tested for its ability to inhibit cAMP production in human glucagon receptor expressed CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed