BDBM50109314 CHEMBL3601683

SMILES COc1ccc(cc1OC)C1=C(C(=O)N(C(=O)c2cc(Br)c(OCc3ccccc3)cc2OC)C1=O)c1ccc(OC)c(OC)c1

InChI Key InChIKey=UQIPIIANKSPVQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109314   

TargetATP-dependent translocase ABCB1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50109314(CHEMBL3601683)
Affinity DataIC50: 25nMAssay Description:Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as paclitaxel IC50 for cell growth inhibition at 1 uM after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed