BDBM50109296 (5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoyl]-methyl}-6-oxo-6,11-dihydro-5H-dibenzo[b,e]azepin-11-yl)-acetic acid::CHEMBL342019

SMILES OC(=O)CC1c2ccccc2N(CC(=O)NCc2ccc(Nc3nc4ccccc4[nH]3)cc2)C(=O)c2ccccc12

InChI Key InChIKey=CBJXBILJNVPTJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109296   

TargetIntegrin alpha-IIb/beta-3(Human)
Knoll

Curated by ChEMBL
LigandPNGBDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of alphaIIb-beta3 integrin from fibrinogen by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL
LigandPNGBDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)
Affinity DataIC50: 7.30nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL
LigandPNGBDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)
Affinity DataIC50: 7nMAssay Description:Affinity against alpha V-beta3 integrin via competitive ELISA using vitronectin as natural ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Knoll

Curated by ChEMBL
LigandPNGBDBM50109296((5-{[4-(1H-Benzoimidazol-2-ylamino)-benzylcarbamoy...)
Affinity DataIC50: 100nMAssay Description:Cell adhesion of alphaV-beta3 integrin expressed in CHO-K1 cell to osteopontin (OPN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed