BDBM50109280 4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-benzo[g]quinoline-3-carbonitrile::CHEMBL132466

SMILES COc1cc2cc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3cc2cc1OC

InChI Key InChIKey=WBPDZLHNIXGYON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109280   

TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)
Affinity DataIC50: 680nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)
Affinity DataIC50: 680nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed