BDBM50109219 4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide::CHEMBL339636

SMILES Cc1cc(cc(C)c1C)-c1c(OCC[C@@H]2CCN2)c2cc(ccc2[nH]c1=O)C(=O)Nc1ccncn1

InChI Key InChIKey=ORQDFXXLMSCLDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50109219   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50109219(4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against human GnRH receptor using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50109219(4-((S)-2-Azetidin-2-yl-ethoxy)-2-oxo-3-(3,4,5-trim...)
Affinity DataIC50: 4nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed