BDBM50109169 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-((S)-1-methyl-2-oxo-ethylcarbamoyl)-2-phenyl-ethyl]-succinamide::CHEMBL126122::N*4*-Hydroxy-2-((S)-isobutyl)-N*1*-[(S)-1-(1-methyl-2-oxo-ethylcarbamoyl)-2-phenyl-ethyl]-succinamide

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C=O

InChI Key InChIKey=FAFCWIZUCJNALJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50109169   

TargetProcathepsin L(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109169((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-((S)-1-met...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Cathepsin L from human kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109169((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-((S)-1-met...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109169((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-((S)-1-met...)
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration against cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109169((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-((S)-1-met...)
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109169((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-((S)-1-met...)
Affinity DataIC50: 25nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProcathepsin L(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109169((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-((S)-1-met...)
Affinity DataIC50: 15nMAssay Description:Inhibition of cathepsin L (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed