BDBM50109051 CHEMBL330529::Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-amine::US10137210, Example [N-methyl-11C]6-Me-BTA-1

SMILES CNc1ccc(cc1)-c1nc2ccc(C)cc2s1

InChI Key InChIKey=GGFYWXBSNMOKOK-UHFFFAOYSA-N

Data  3 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109051   

TargetAlpha-synuclein(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50109051(Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-ami...)
Affinity DataKd:  300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMicrotubule-associated protein tau(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50109051(Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-ami...)
Affinity DataKd:  2.55E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50109051(Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-ami...)
Affinity DataKi:  10nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50109051(Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-ami...)
Affinity DataKi:  20nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50109051(Methyl-[4-(6-methyl-benzothiazol-2-yl)-phenyl]-ami...)
Affinity DataKi:  21nMAssay Description:Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent