BDBM50108856 CHEMBL103238::benzyl (S)-1-oxo-1-((S)-3-oxo-1-phenyl-4-(3-phenylpropylthio)butan-2-ylamino)-3-phenylpropan-2-ylcarbamate::{(S)-1-[(S)-1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester::{1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)CSCCCc1ccccc1)OCc1ccccc1

InChI Key InChIKey=AFTKDSGGPNEFNN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50108856   

TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50108856({1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-pro...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against cruzain, the major cysteine protease found in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50108856({1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-pro...)
Affinity DataKi:  2nMAssay Description:Affinity for cysteine protease (Cruzipain) of Chagas' diseaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California

Curated by ChEMBL
LigandPNGBDBM50108856({1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-pro...)
Affinity DataKi:  2nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50108856({1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-pro...)
Affinity DataKi:  2.80nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50108856({1-[1-Benzyl-2-oxo-3-(3-phenyl-propylsulfanyl)-pro...)
Affinity DataKi:  45.4nMAssay Description:Inhibitory activity against human Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed