BDBM50108748 CHEMBL358327::[4-(4-Isoquinolin-1-yl-piperazin-1-yl)-pyrimidin-2-yl]-methanol

SMILES OCc1nccc(n1)N1CCN(CC1)c1nccc2ccccc12

InChI Key InChIKey=IQCFOZXJRKINGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108748   

TargetSorbitol dehydrogenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108748([4-(4-Isoquinolin-1-yl-piperazin-1-yl)-pyrimidin-2...)
Affinity DataIC50: 430nMAssay Description:Concentration required for 50% in vitro inhibition in sheep liver sorbitol dehydrogenase (s-SDH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSorbitol dehydrogenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108748([4-(4-Isoquinolin-1-yl-piperazin-1-yl)-pyrimidin-2...)
Affinity DataIC50: 150nMAssay Description:Concentration required for 50% in vitro inhibition of recombinant human sorbitol dehydrogenase (h-SDH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed