BDBM50108713 1'-phenethylspiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]::CHEMBL148418

SMILES C(Cc1ccccc1)N1CCC2(CC1)CCc1ccccc1O2

InChI Key InChIKey=HAULFEWWRJNEKX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108713   

Target5-hydroxytryptamine receptor 2A(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108713(1'-phenethylspiro[3,4-dihydro-2H-chromene-2,4'-(he...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for displacement of [3H]ketanserin to rat 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108713(1'-phenethylspiro[3,4-dihydro-2H-chromene-2,4'-(he...)
Affinity DataKi:  16nMAssay Description:Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108713(1'-phenethylspiro[3,4-dihydro-2H-chromene-2,4'-(he...)
Affinity DataKi:  530nMAssay Description:Binding affinity for displacement of [3H]spiperone to human dopamine D2 (hD2) receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed