BDBM50108668 1'-benzyl-3-ethoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]::CHEMBL138102

SMILES CCOC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1

InChI Key InChIKey=YMCQNFKWAUISDZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108668   

TargetSigma non-opioid intracellular receptor 1(Human)
Pharmazeutisches Institut Der UniversitäT Freiburg

Curated by ChEMBL
LigandPNGBDBM50108668(1'-benzyl-3-ethoxyspiro[3,4-dihydro-1H-isochromene...)
Affinity DataKi:  5.80nMAssay Description:Sigma opioid receptor type 1 affinity in guinea pig brain by employing [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Pharmazeutisches Institut Der UniversitäT Freiburg

Curated by ChEMBL
LigandPNGBDBM50108668(1'-benzyl-3-ethoxyspiro[3,4-dihydro-1H-isochromene...)
Affinity DataKi:  2.96E+3nMAssay Description:Sigma opioid receptor type 2 affinity in rat liver by employing [3H]ditolylguanidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed