BDBM50108627 CHEMBL3597951

SMILES Fc1ccc(cc1)S(=O)(=O)N(Cc1ncc[nH]1)c1ccccc1-c1ccccc1

InChI Key InChIKey=PCDMCECXKAELMI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108627   

TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50108627(CHEMBL3597951)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to recombinant human orexin-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50108627(CHEMBL3597951)
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]-orexin A recombinant human OX2R expressed in HEK293 cells assessed as inhibition constant incubated for 90 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50108627(CHEMBL3597951)
Affinity DataKi:  393nMAssay Description:Binding affinity to recombinant human orexin-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50108627(CHEMBL3597951)
Affinity DataKi:  393nMAssay Description:Displacement of [125I]-orexin A recombinant human OX1R expressed in HEK293 cells assessed as inhibition constant incubated for 90 mins by scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed