BDBM50108441 3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one::CHEMBL278268

SMILES O=c1c(cccn1C(CN1CCCC1)c1ccccc1)-c1ccccc1

InChI Key InChIKey=CMEOQHOBYZAUEU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50108441   

TargetKappa-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 56nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 56nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 56nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]Enkephalin binding to human mu opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards mu opioid receptor by the displacement of [125I]EnkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]deltorphin binding to human delta opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]Enkephalin binding to human mu opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [125I]-DeltorphinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125I]deltorphin binding to human delta opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed