BDBM50108376 CHEMBL54894::N-{5-Chloro-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-pyridin-2-yl}-guanidine

SMILES [#6]-[#8]-c1ccc(-[#6]=[#6]-c2cc(Cl)cnc2\[#7]=[#6](\[#7])-[#7])cc1

InChI Key InChIKey=JUARJLCQEFFZOF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108376   

TargetUrokinase-type plasminogen activator(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108376(N-{5-Chloro-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-pyr...)
Affinity DataKi:  690nMAssay Description:In vitro inhibition of human urokinase Plasminogen Activator.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108376(N-{5-Chloro-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-pyr...)
Affinity DataKi:  4.25E+4nMAssay Description:Ability to inhibit plasmin using human plasmin (quadratech) and Chromozym-PL (boehringer) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108376(N-{5-Chloro-3-[(E)-2-(4-methoxy-phenyl)-vinyl]-pyr...)
Affinity DataKi:  6.01E+4nMAssay Description:Ability to inhibit tissue plasminogen activator (quadratech) and S-2444 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed