BDBM50108348 CHEMBL296922::Indole Derivative

SMILES COc1ccc2CC3C4[C@@H](C)c5c([nH]c6ccccc56)[C@@H]5Oc1c2C45CCN3C

InChI Key InChIKey=CQDVKAKVXRIKJR-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50108348   

TargetDelta-type opioid receptor(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50108348(Indole Derivative | CHEMBL296922)
Affinity DataKi:  27nMAssay Description:Binding affinity for delta opioid receptor by displacing [3H]DADL was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50108348(Indole Derivative | CHEMBL296922)
Affinity DataKi:  330nMAssay Description:Binding affinity for gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Niddk

Curated by ChEMBL
LigandPNGBDBM50108348(Indole Derivative | CHEMBL296922)
Affinity DataKi: >350nMAssay Description:Binding affinity for kappa opioid receptor by displacing U-69,593 was determined in [35S]-GTP gamma-S binding assay; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Niddk

Curated by ChEMBL
LigandPNGBDBM50108348(Indole Derivative | CHEMBL296922)
Affinity DataKi: >350nMAssay Description:Binding affinity for kappa opioid receptor by displacing U-69,593 was determined in [35S]-GTP gamma-S binding assay; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Niddk

Curated by ChEMBL
LigandPNGBDBM50108348(Indole Derivative | CHEMBL296922)
Affinity DataKi: >600nMAssay Description:Binding affinity for mu opioid receptor by displacing DAMGO was determined in [35S]-GTP gamma-S binding assay; InactiveMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Niddk

Curated by ChEMBL
LigandPNGBDBM50108348(Indole Derivative | CHEMBL296922)
Affinity DataKi: >4.80E+3nMAssay Description:Binding affinity for mu opioid receptor by displacing [3H]-DAMGO was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed