BDBM50108204 3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22513

SMILES CCOc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1

InChI Key InChIKey=UEHPBBFVUYURNP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108204   

TargetEndothelin-1 receptor(Human)TBA
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50: 0.550nMAssay Description:Displacement of [I125]ET1 from Homo sapiens (human) ETA receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetEndothelin-1 receptor(Human)TBA
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50: 0.550nMAssay Description:Displacement of [125I]-labeled ET-1 from human cloned endothelin A (ETA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50: 397nMAssay Description:Binding affinity towards human cloned endothelin B receptor by [125I]ET1 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50108204(3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-be...)
Affinity DataIC50: 397nMAssay Description:Displacement of [I125]ET1 from Homo sapiens (human) ETB receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article