BDBM50108155 CHEMBL73928::N-Hydroxy-N-{1-pyridin-2-yl-2-[4-(4-trifluoromethoxy-phenoxy)-benzenesulfonyl]-ethyl}-formamide

SMILES ON(C=O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccccn1

InChI Key InChIKey=YHQIGEQPWJUUHA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50108155   

TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108155(N-Hydroxy-N-{1-pyridin-2-yl-2-[4-(4-trifluorometho...)
Affinity DataIC50: 2.20nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108155(N-Hydroxy-N-{1-pyridin-2-yl-2-[4-(4-trifluorometho...)
Affinity DataIC50: 1.70nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108155(N-Hydroxy-N-{1-pyridin-2-yl-2-[4-(4-trifluorometho...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50108155(N-Hydroxy-N-{1-pyridin-2-yl-2-[4-(4-trifluorometho...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed