BDBM50108064 4'-(3-Mercapto-benzoylamino)-[1,1';2',1'']terphenyl-3-carboxylic acid 34(FTI-2313)::CHEMBL55306

SMILES OC(=O)c1cccc(c1)-c1ccc(NC(=O)c2cccc(S)c2)cc1-c1ccccc1

InChI Key InChIKey=GAXUPYKSAAWHPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108064   

LigandPNGBDBM50108064(4'-(3-Mercapto-benzoylamino)-[1,1';2',1'']terpheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50108064(4'-(3-Mercapto-benzoylamino)-[1,1';2',1'']terpheny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed