BDBM50108003 6-(Isoquinolin-5-ylaminomethyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL346666

SMILES Cc1c(CNc2cccc3cnccc23)cnc2nc(N)nc(N)c12

InChI Key InChIKey=XKJJYOOQKZJMEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50108003   

TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50108003(6-(Isoquinolin-5-ylaminomethyl)-5-methyl-pyrido[2,...)
Affinity DataIC50: 4nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50108003(6-(Isoquinolin-5-ylaminomethyl)-5-methyl-pyrido[2,...)
Affinity DataIC50: 0.870nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex dihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed