BDBM50107990 CHEMBL359144::xv5-Methyl-6-(pyren-1-ylaminomethyl)-pyrido[2,3-d]pyrimidineamine

SMILES Cc1c(CNc2ccc3ccc4cccc5ccc2c3c45)cnc2nc(N)nc(N)c12

InChI Key InChIKey=ZXPLJUACCJOOLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107990   

TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107990(xv5-Methyl-6-(pyren-1-ylaminomethyl)-pyrido[2,3-d]...)
Affinity DataIC50: 3.80nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107990(xv5-Methyl-6-(pyren-1-ylaminomethyl)-pyrido[2,3-d]...)
Affinity DataIC50: 0.880nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex dihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed