BDBM50107975 6-[(2,5-Dipropoxy-phenylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL151312

SMILES CCCOc1ccc(OCCC)c(NCc2cnc3nc(N)nc(N)c3c2C)c1

InChI Key InChIKey=RQIHFVXPJYOCDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107975   

TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107975(6-[(2,5-Dipropoxy-phenylamino)-methyl]-5-methyl-py...)
Affinity DataIC50: 1nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex dihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107975(6-[(2,5-Dipropoxy-phenylamino)-methyl]-5-methyl-py...)
Affinity DataIC50: 7.30E+3nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed