BDBM50107961 5-Methyl-6-(quinolin-6-ylaminomethyl)-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL147469

SMILES Cc1c(CNc2ccc3ncccc3c2)cnc2nc(N)nc(N)c12

InChI Key InChIKey=ZRQCALAJVPEFAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107961   

TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107961(5-Methyl-6-(quinolin-6-ylaminomethyl)-pyrido[2,3-d...)
Affinity DataIC50: 7.10nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50107961(5-Methyl-6-(quinolin-6-ylaminomethyl)-pyrido[2,3-d...)
Affinity DataIC50: 0.950nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex dihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed