BDBM50107800 CHEMBL356126::{2-[(4'-Chloro-6-methyl-biphenyl-2-carbonyl)-amino]-6,7,8,9-tetrahydro-5H-benzocyclohepten-7-yl}-carbamic acid methyl ester

SMILES COC(=O)NC1CCc2ccc(NC(=O)c3cccc(C)c3-c3ccc(Cl)cc3)cc2CC1

InChI Key InChIKey=OLXBRQXHOJCVJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107800   

TargetMicrosomal triglyceride transfer protein large subunit(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107800({2-[(4'-Chloro-6-methyl-biphenyl-2-carbonyl)-amino...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApolipoprotein B-100(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107800({2-[(4'-Chloro-6-methyl-biphenyl-2-carbonyl)-amino...)
Affinity DataIC50: 2nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed