BDBM50107794 CHEMBL356937::{5-[(4,4'-Bis-trifluoromethyl-biphenyl-2-carbonyl)-amino]-indan-2-yl}-carbamic acid methyl ester

SMILES COC(=O)N[C@H]1Cc2ccc(NC(=O)c3cc(ccc3-c3ccc(cc3)C(F)(F)F)C(F)(F)F)cc2C1

InChI Key InChIKey=ZPTKJYMGKHTPFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107794   

TargetMicrosomal triglyceride transfer protein large subunit(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107794({5-[(4,4'-Bis-trifluoromethyl-biphenyl-2-carbonyl)...)
Affinity DataIC50: 410nMAssay Description:In vitro inhibitory activity against MTP using MTP transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetApolipoprotein B-100(Human)
Novartis Institute For Biomedical Reasearch

Curated by ChEMBL
LigandPNGBDBM50107794({5-[(4,4'-Bis-trifluoromethyl-biphenyl-2-carbonyl)...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed