BDBM50107743 [(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-butyl}-phenyl)-difluoro-methyl]-phosphonic acid

SMILES [O-]P([O-])(=O)C(F)(F)c1ccc(CCCCc2ccc(cc2)C(F)(F)P([O-])([O-])=O)cc1

InChI Key InChIKey=SRHSAABKYJDBDV-UHFFFAOYSA-J

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50107743   

TargetTyrosine-protein phosphatase non-receptor type 6(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50107743([(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-buty...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase SHP-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50107743([(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-buty...)
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase CD45.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50107743([(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-buty...)
Affinity DataIC50: 3.42E+5nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase PTPbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50107743([(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-buty...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase TCPTP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50107743([(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-buty...)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase SHP-2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50107743([(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-buty...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50107743([(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-buty...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity towards the site of PTP1B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed