BDBM50107710 1,12-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)-1,2,5-thiadiazol-3-ylsulfanyl]dodecane::CHEMBL139603

SMILES CN1CCC=C(C1)c1nsnc1SCCCCCCCCCCCCSc1nsnc1C1=CCCN(C)C1

InChI Key InChIKey=ZQCPQPVEHGBNPZ-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50107710   

TargetMuscarinic acetylcholine receptor M1(Human)
The University of Toledo

Curated by ChEMBL
LigandPNGBDBM50107710(1,12-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl...)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonistic activity against M1 muscarinic receptor expressed in A9 L cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
The University of Toledo

Curated by ChEMBL
LigandPNGBDBM50107710(1,12-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl...)
Affinity DataEC50:  1nMAssay Description:Agonist activity against M4 muscarinic receptor expressed in RBL-2H3 Mast cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
The University of Toledo

Curated by ChEMBL
LigandPNGBDBM50107710(1,12-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity towards M1 muscarinic receptor expressed in A9 L cells by displacing [3H](R)-QNB radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed