BDBM50107492 4-[2-(4-Fluoro-benzylsulfanyl)-5-(2-methoxy-pyrimidin-5-ylmethyl)-4-oxo-4H-pyrimidin-1-yl]-N-(4'-fluoro-biphenyl-4-ylmethyl)-N-methyl-butyramide::CHEMBL153374

SMILES COc1ncc(Cc2cn(CCCC(=O)N(C)Cc3ccc(cc3)-c3ccc(F)cc3)c(SCc3ccc(F)cc3)nc2=O)cn1

InChI Key InChIKey=OBLSLHHZZMQGAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107492   

TargetPlatelet-activating factor acetylhydrolase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50107492(4-[2-(4-Fluoro-benzylsulfanyl)-5-(2-methoxy-pyrimi...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against recombinant human Lp-PLA2 (Lp-PLA2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed