BDBM50107343 (4-Chloro-butyl)-methyl-phosphoramidic acid 5-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 5-nitro-furan-2-ylmethyl ester::CHEMBL139442

SMILES CN(CCCCCl)P(=O)(OCC1OC(CC1O)n1cc(F)c(=O)[nH]c1=O)OCc1ccc(o1)[N+]([O-])=O

InChI Key InChIKey=QJSUJNHXESNBMF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107343   

TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107343((4-Chloro-butyl)-methyl-phosphoramidic acid 5-(5-f...)
Affinity DataIC50: 65nMAssay Description:Thymidylate synthase inhibition in L1210 mouse leukemia cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107343((4-Chloro-butyl)-methyl-phosphoramidic acid 5-(5-f...)
Affinity DataIC50: 1.06E+3nMAssay Description:Thymidylate synthase inhibition in thymidine kinase deficient LM cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107343((4-Chloro-butyl)-methyl-phosphoramidic acid 5-(5-f...)
Affinity DataIC50: 560nMAssay Description:Thymidylate synthase inhibition in wild type LM cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107343((4-Chloro-butyl)-methyl-phosphoramidic acid 5-(5-f...)
Affinity DataIC50: 1.90nMAssay Description:Thymidylate synthase inhibition in thymidine kinase deficient /TK cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed