BDBM50107341 (4-Chloro-butyl)-methyl-phosphoramidic acid 1,4-dioxo-1,4-dihydro-naphthalen-2-ylmethyl ester 5-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester::CHEMBL138915

SMILES CN(CCCCCl)P(=O)(OCC1OC(CC1O)n1cc(F)c(=O)[nH]c1=O)OCC1=CC(=O)c2ccccc2C1=O

InChI Key InChIKey=VIOXADGCOMQISB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107341   

TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107341((4-Chloro-butyl)-methyl-phosphoramidic acid 1,4-di...)
Affinity DataIC50: 5.90E+3nMAssay Description:Thymidylate synthase inhibition in thymidine kinase deficient LM cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107341((4-Chloro-butyl)-methyl-phosphoramidic acid 1,4-di...)
Affinity DataIC50: 230nMAssay Description:Thymidylate synthase inhibition in wild type LM cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107341((4-Chloro-butyl)-methyl-phosphoramidic acid 1,4-di...)
Affinity DataIC50: 25nMAssay Description:Thymidylate synthase inhibition in thymidine kinase deficient /TK cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50107341((4-Chloro-butyl)-methyl-phosphoramidic acid 1,4-di...)
Affinity DataIC50: 10nMAssay Description:Thymidylate synthase inhibition in L1210 mouse leukemia cells after 2 hr treatmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed