BDBM50106896 CHEMBL104708::N-[(E)-(R)-1-(4,5-Dichloro-thiophen-2-ylmethyl)-3-((R)-2-oxo-azepan-3-ylcarbamoyl)-allyl]-N-methyl-3,5-bis-trifluoromethyl-benzamide

SMILES CN([C@H](Cc1cc(Cl)c(Cl)s1)\C=C\C(=O)N[C@@H]1CCCCNC1=O)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=QNABWLPZWWNWJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106896   

TargetSubstance-P receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50106896(N-[(E)-(R)-1-(4,5-Dichloro-thiophen-2-ylmethyl)-3-...)
Affinity DataIC50: 3.60nMAssay Description:In vitro binding affinity for Tachykinin receptor 1 of bovine retinal membranes using [3H]Sar9-substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50106896(N-[(E)-(R)-1-(4,5-Dichloro-thiophen-2-ylmethyl)-3-...)
Affinity DataIC50: 17nMAssay Description:In vitro binding affinity for Tachykinin receptor 2 of human-CHO cells using 125 I-NKA radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed