BDBM50106663 6,6,6-Trifluoro-3-(formyl-hydroxy-amino)-2-isobutyl-hexanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-2-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL334567

SMILES CC(C)C[C@H]([C@H](CCC(F)(F)F)N(O)C=O)C(=O)N[C@@H]([C@H](C)CCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1

InChI Key InChIKey=KIKBZIXCMWKZEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106663   

TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106663(6,6,6-Trifluoro-3-(formyl-hydroxy-amino)-2-isobuty...)
Affinity DataIC50: 22nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106663(6,6,6-Trifluoro-3-(formyl-hydroxy-amino)-2-isobuty...)
Affinity DataIC50: 52nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106663(6,6,6-Trifluoro-3-(formyl-hydroxy-amino)-2-isobuty...)
Affinity DataIC50: 17nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106663(6,6,6-Trifluoro-3-(formyl-hydroxy-amino)-2-isobuty...)
Affinity DataIC50: 8nMAssay Description:Inhibition of TACE using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed