BDBM50106662 3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cyclohexylmethyl)-pentanoic acid [4-{[amino-(pyridine-2-sulfonylimino)-methyl]-amino}-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL135983

SMILES CC(C)[C@@H]([C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](CCCN=C(N)NS(=O)(=O)c1ccccn1)C(=O)Nc1nccs1)N(O)C=O

InChI Key InChIKey=UBBKFTZMBAKVDC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106662   

TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106662(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 71nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106662(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 115nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106662(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 96nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106662(3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cycl...)
Affinity DataIC50: 16nMAssay Description:Inhibition of TACE using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed