BDBM50106656 3-(Formyl-hydroxy-amino)-2-isobutyl-hexanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL263459::TCMDC-138171

SMILES CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1)N(O)C=O

InChI Key InChIKey=ZLIOUDYFRDHHSM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106656   

TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106656(TCMDC-138171 | 3-(Formyl-hydroxy-amino)-2-isobutyl...)
Affinity DataIC50: 51nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50106656(TCMDC-138171 | 3-(Formyl-hydroxy-amino)-2-isobutyl...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of TACE using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106656(TCMDC-138171 | 3-(Formyl-hydroxy-amino)-2-isobutyl...)
Affinity DataIC50: 122nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50106656(TCMDC-138171 | 3-(Formyl-hydroxy-amino)-2-isobutyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed