BDBM50106508 7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-quinoline-5,8-dione::CHEMBL336095

SMILES Oc1cc(N=CCc2cc(Br)c(O)c(Br)c2)c(O)c2ncccc12

InChI Key InChIKey=NKWFSWJBTHPLIV-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106508   

TargetDual specificity protein phosphatase 3(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106508(7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibitory Activity against Recombinant Human VHRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106508(7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...)
Affinity DataIC50: 640nMAssay Description:Inhibitory activity against recombinant human cell division cycle 25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50106508(7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory Activity against Recombinant Human PTP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEzrin(Human)
George Mason University

Curated by ChEMBL
LigandPNGBDBM50106508(7-[2-(3,5-Dibromo-4-hydroxy-phenyl)-ethylamino]-qu...)
Affinity DataKd:  1.06E+4nMAssay Description:Binding affinity to recombinant ezrin (unknown origin) by surface plasmon resonance spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed